半岛bd体育手机客户端 说明
生化/生理作用
Anti Trypanosoma, Leishmania agent.
Fexinidazole is a potent anti-Trypanosoma agent. Trypanosoma species human protozoan pathogens are responsible for sleeping sickness and Chagas disease.In vivo, fexinidazole is oxidized to sulfoxide and sulfone metabolites that are effective in blocking the progression of the parasitic disease visceral leishmaniasis. The mechanism of action appears to be by reductive activationviaan NADH-dependent nitroreductase expressed by the parasites.
基本信息
| 经验(实验)分子式 | C12H13N3O3S |
| 分子量 | 279.31 |
| MDL编号 | MFCD00866607 |
半岛bd体育手机客户端 性质
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 颜色 | light yellow to dark brown |
| 溶解性 | DMSO: 2 mg/mL, clear |
| 储存温度 | ?20℃ |
| SMILES string | CN1C(COC2=CC=C(SC)C=C2)=NC=C1[N+]([O-])=O |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
