EVP4593 - 半岛电竞官方网址

EVP4593

品牌

Sigma-Aldrich

CAS

545380-34-5

货号

SML0579

包装型号

规格纯度

≥98% (HPLC)

价格

1503.51 元 *本价格含增值税费

促销

数量

- +

半岛bd体育手机客户端名称：

545380-34-5
EVP4593
QNZ
4-N-[2-(4-Phenoxyphenyl)ethyl]quinazoline-4,6-diamine
N4-[2-(4-Phenoxyphenyl)ethyl]-4,6-quinazolinediamine

半岛bd体育手机客户端介绍：

半岛bd体育手机客户端说明

包装

5, 25 mg in glass bottle

生化/生理作用

EVP4593 is a high affinity partial antagonist of NF -K B pathway activation acting by inhibiting store-operated calcium (Ca²⁺) entry (SOC). It appears that EVP4593 targets heteromeric channels containing TRPC1 as one of the subunits in HD neurons. EVP4593 exhibits neuroprotective effects from glutamate toxicity in nanomolar concentrations.

特点和优势

This compound is featured on the Calcium Channels, Cytokine Receptors (Interleukin-1 Receptor/TIR Family) and Cytokine Receptors (Tumor Necrosis Receptor Family) pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

其他说明

Air sensitive

基本信息

经验(实验)分子式	C₂₂H₂₀N₄O
分子量	356.42
MDL编号	MFCD06411436
PubChem化学物质编号	329825563
NACRES	NA.77

半岛bd体育手机客户端性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
储存条件	desiccated
颜色	white to beige
溶解性	DMSO: 15 mg/mL, clear
储存温度	2-8℃
SMILES string	NC1=CC(C(NCCC2=CC=C(OC3=CC=CC=C3)C=C2)=NC=N4)=C4C=C1
InChI	1S/C22H20N4O/c23-17-8-11-21-20(14-17)22(26-15-25-21)24-13-12-16-6-9-19(10-7-16)27-18-4-2-1-3-5-18/h1-11,14-15H,12-13,23H2,(H,24,25,26)
InChI key	IBAKVEUZKHOWNG-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable