EIDD 1931 5′-isopropylester - 半岛电竞官方网址

EIDD-2801

品牌

Sigma-Aldrich

CAS

2349386-89-4

货号

SML2873

包装型号

规格纯度

≥98% (HPLC)

价格

1042.98 元 *本价格含增值税费

促销

数量

- +

半岛bd体育手机客户端名称：

2349386-89-4
EIDD-2801
EIDD2801
EIDD 1931 5′-isopropylester
N4-Hydroxycytidine 5′-isopropylester
beta-D-N4-Hydroxycytidine 5′-isopropylester
EIDD 1931 prodrug
N4OHcyd ester
4-N-HO-Cyd ester
EIDD1931 prodrug
EIDD-1931 prodrug
N4-OHcyd ester
(oh)4Cyd lester
NHC ester
EIDD-1931 5′-isopropylester
EIDD1931 5′-isopropylester
EIDD 2801
((2R,3S,4R,5R)-3,4-Dihydroxy-5-(4-(hydroxyamino)-2-oxopyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl isobutyrate
BHC ester

半岛bd体育手机客户端介绍：

半岛bd体育手机客户端说明

生化/生理作用

EIDD-2801 is an orally active, 5′-isopropylester prodrug form of the antiviral ribonucleoside analog N4-hydroxycytidine (NHC, EIDD-1931) with known anti-viral activity against SARS-CoV, SARS-CoV-2, RSV, influenza A & B (IAV & IBV), HCV, pestivirus, bovine viral diarrhoea virus (BVDV), Ebola (EBOV), Chikungunya (CHIKV), venezuelan equine encephalitis (VEEV). EIDD-2801 is efficiently hydrolyzed to NHCin vivo, being more orally bioavailable than NHC in nonhuman primates and ferrets, while maintaining similar oral bioavailability as NHC in mice. EIDD-2801 displaysin vivoefficacy against pandemic and seasonal IAV strains in ferrets (lowest ED = 2.3 and 7 mg/kg b.i.d. p.o., respectively).

基本信息

经验(实验)分子式	C₁₃H₁₉N₃O₇
分子量	329.31

半岛bd体育手机客户端性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 2 mg/mL, clear
储存温度	?20℃

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable