半岛bd体育手机客户端 说明

应用

Ara-G is converted by cellular kinases to the active 5′-triphosphate, Ara-GTP. This active form of Ara-G induces apoptosis and inhibits DNA synthesis. Ara-G is also an antineoplastic and antimetabolite.

包装

5, 25 mg in glass bottle

生化/生理作用

Ara-G is an inducer of apoptosis; inhibitor of DNA synthesis; antineoplastic; and antimetabolite. Ara-G is converted by cellular kinases to the active 5′-triphosphate, Ara-GTP. Incorporation of Ara-GTP into DNA leads to inhibition of DNA synthesis and apoptosis.

基本信息

经验(实验)分子式	C10H13N5O5· xH2O
分子量	283.24 (anhydrous basis)
MDL编号	MFCD00065486
PubChem化学物质编号	329770852
NACRES	NA.77

半岛bd体育手机客户端 性质

质量水平	100
测定	≥98% (HPLC)
形式	solid
溶解性	DMSO: >10 mg/mL H2O: insoluble
储存温度	2-8℃
SMILES string	NC1=Nc2c(ncn2[C@@H]3O[C@H](CO)[C@@H](O)[C@@H]3O)C(=O)N1
InChI	1S/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6+,9-/m1/s1
InChI key	NYHBQMYGNKIUIF-FJFJXFQQSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302 - H315 - H319 - H335
预防措施声明	P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338
危险分类	Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves