半岛bd体育手机客户端 说明
一般描述
O-Desmethyl gefitinib is a major active metabolite of gefitinib. It is a potent EGFR (erbB1/HER1) inhibitor (IC50 = 36 nM). Gefitinib is metabolized by CYP2D6 toO-Desmethyl gefitinib. Gefitinib is an EGFR inhibitor that is used to treat some types of cancers.
应用
Metabolomics research
基本信息
经验(实验)分子式 | C21H22ClFN4O3 |
分子量 | 432.88 |
半岛bd体育手机客户端 性质
质量水平 | 100 |
生物来源 | synthetic |
等级 | research grade |
测定 | ≥95% |
形式 | solid |
technique(s) | HPLC: suitable |
颜色 | light yellow to yellow |
储存温度 | ?20℃ |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H302 - H315 - H319 - H335 |
预防措施声明 | P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338 |
危险分类 | Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
靶器官 | Respiratory system |
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich