半岛bd体育手机客户端 说明

一般描述

3-Methyl-2-oxindole (MOI) is a 3-substituted-2-oxindole. It is reported to be formed during the oxidation of indole-3-acetic acid in the presence of Fe^IIunder aerobic conditions. MOI undergoes asymmetricanti-Mannich-type reaction withN-tosyl aryl aldimines in the presence of alkaloid cinchona derivatives to form anti-3,3-disubsituted 2-oxindole derivatives. It also undergoes asymmetric hydroxyamination with nitrosoarenes to formN-nitroso aldol products.

应用

3-Methyl-2-oxindole may be used in the preparation of 3-hydroxy-3-methyl-2-oxindole.

• Reactant for enantioselective α-amination reactions
• Reactant for aldol reaction with glyoxal derivatives
• Reactant for amine thiourea catalyzed conjugate addition to α,β-unsaturated aldehydes
• Reactant for O-acetylation reactions
• Reactant for preparation of a disubstituted oxoindole by using rhodium-catalyzed cyclopropanation/ring-opening reactions

包装

5, 25 g in glass bottle

基本信息

经验(实验)分子式	C9H9NO
分子量	147.17
MDL编号	MFCD04037370
PubChem化学物质编号	24872867
NACRES	NA.22

半岛bd体育手机客户端 性质

质量水平	100
测定	96%
mp	117-121 ℃ (lit.)
SMILES string	CC1C(=O)Nc2ccccc12
InChI	1S/C9H9NO/c1-6-7-4-2-3-5-8(7)10-9(6)11/h2-6H,1H3,(H,10,11)
InChI key	BBZCPUCZKLTAJQ-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)