AH6809

半岛bd体育手机客户端 说明

应用

AH6809 has been used:

• as a prostaglandin E2 receptor 1 & 2 (EP1/2) antagonist to analyze its effects on cyclooxygenase-2 /prostaglandin E2 (COX-2/PGE2) signaling in the angiogenic feedback of endothelial cells to hypoxia
• as an EP2 antagonist to study its effects on tumor angiogenesis in human prostate cancer cell lines
• as an EP2 antagonist to analyze its effects on overexpression of amyloid precursor protein (APP)

包装

5 mg in glass bottle

生化/生理作用

AH6809 plays a role in antagonizing the proliferation of non-small cell lung cancer cell lines.
DP/EP prostanoid receptor antagonist; has the highest affinity for DP receptors, but also acts as a weak antagonist at murine EP₁and EP₂prostanoid receptors.

特点和优势

This compound is featured on the Prostanoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式	C17H14O5
分子量	298.29
MDL编号	MFCD08056083
PubChem化学物质编号	329770690
NACRES	NA.77

半岛bd体育手机客户端 性质

质量水平	100
测定	≥98%
形式	crystalline solid or supercooled liquid
溶解性	ethanol: soluble 2.5 mg/mL DMSO or DMF: soluble 8 mg/mL
SMILES string	CC(C)Oc1ccc2c(Oc3ccc(cc3C2=O)C(O)=O)c1
InChI	1S/C17H14O5/c1-9(2)21-11-4-5-12-15(8-11)22-14-6-3-10(17(19)20)7-13(14)16(12)18/h3-9H,1-2H3,(H,19,20)
InChI key	AQFFXPQJLZFABJ-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)