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位置: 首页> 品牌> Sigma-Aldrich> Anti-PRL-2 Antibody, clone 42

Anti-PRL-2 Antibody, clone 42

品牌
Sigma-Aldrich
货号
05-1583
规格纯度
clone 42, from mouse
价格
5520.38 *本价格含增值税费
促销
服务
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  • 增值税票
数量
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半岛bd体育手机客户端 名称:
Anti-PRL-2 Antibody, clone 42
Protein-tyrosine phosphatase 4a2, Protein-tyrosine phosphatase of regenerating liver 2, phosphatase of regenerating liver 2, protein tyrosine phosphatase IVA, protein tyrosine phosphatase IVA2, protein tyrosine phosphatase type IVA, member 2
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

PRL-2 is one of three members (PRL-1, PRL-2, and PRL-3) that is part of a unique protein-tyrosine phosphatase ((PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP is known to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferres a transformed phenotype and can result in a tumor growth in nude mice, suggesting a role in tumorigenesis. Alternatively spliced transcript variants that encode two distinct isoforms have been described

特异性

This antibody recognizes PRL-2.

免疫原

Epitope: Unknown
GST-tagged recombinant protein corresponding to mouse PRL-2.

应用

Research Sub Category
Cell Cycle, DNA Replication & Repair
Research Category
Epigenetics & Nuclear Function
Anti-PRL-2 Antibody, clone 42 detects level of PRL-2 & has been published & validated for use in WB, IH & IP.
Immunohistochemistry Analysis:
A representative lot was used by an independent laboratory in IH.
Immunoprecipitation Analysis:
A representative lot was used by an independent laboratory in IP.

质量

Evaluated by Western Blot in HeLa cell lysate.
Western Blot Analysis: 0.5 ?g/ml of this antibody detected PRL-2 on 10 ?g of HeLa cell lysate.

目标描述

~ 19 kDa

外形

Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.
Format: Purified
Protein G Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
HeLa cell lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 mouse
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 42, monoclonal
species reactivity human
species reactivity (predicted by homology) mouse (based on 100% sequence homology)
technique(s) immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
同位素/亚型 IgG2bκ
NCBI登记号 NP_001158217.1
UniProt登记号 O70274
运输 wet ice

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

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