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位置: 首页> 品牌> Sigma-Aldrich> Anti-HDAC3 Antibody, clone 3G6

Anti-HDAC3 Antibody, clone 3G6

品牌
Sigma-Aldrich
货号
05-813
规格纯度
clone 3G6, Upstate?, from mouse
价格
6694.05 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
Anti-HDAC3 Antibody, clone 3G6
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC3 belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. HDAC3 is regarded as a potential tumor suppressor gene.

特异性

Predicted to cross-react with rat and chicken based on sequence homology
HDAC3

免疫原

peptide (NEFYDGDHDNDKESDVEI) corresponding to amino acids 411-428 of human HDAC3

应用

Research Sub Category
Histones
Anti-HDAC3 Antibody, clone 3G6 is a Mouse Monoclonal Antibody for detection of HDAC3 also known as histone deacetylase 3 & has been tested in IP, WB, ICC.
Research Category
Epigenetics & Nuclear Function

质量

routinely evaluated by immunoprecipitation/HDAC

目标描述

49-53kDa

外形

0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%.
Format: Purified
Protein G Purified

储存及稳定性

2 years at -20°C

分析说明

Control
HL-60 cell lysate

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 mouse
抗体形式 purified antibody
antibody product type primary antibodies
克隆 3G6, monoclonal
species reactivity human, bovine, mouse, hamster
manufacturer/tradename Upstate?
technique(s) immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
同位素/亚型 IgG2a
NCBI登记号 NM_003883
UniProt登记号 O15379
运输 wet ice

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 1

Sigma-Aldrich

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