Anti-Fibroblast Growth Factor Receptor 1 Antibody, clone VBS1

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一般描述

The fibroblast growth factor receptors are members of the tyrosine kinase superfamily and consist of an extracellular ligand domain composed of three immunoglobulin-like domains, a single transmembrane helix domain, and an intracellular domain with tyrosine kinase activity. (Ornitz, DM. and Itoh, N) Monoclonal antibodies against the high affinity tyrosine kinase Fibroblast Growth Factor (FGF) receptor may help define receptor epitopes involved in FGF binding and signal transduction which mediate coronary and tumor angiogenesis. (Venkateswaran, S., et al).

特异性

This antibody recognizes the extracellular ligand-binding domain of Fibroblast Growth Factor Receptor 1.

免疫原

FGF Receptor purified from bovine coronary venular endothelial cells.
Epitope: Extracellular

应用

Detect Fibroblast Growth Factor Receptor 1 using this Anti-Fibroblast Growth Factor Receptor 1 Antibody, clone VBS1 validated for use in WB, IP, IH(P), ELISA.
Research Sub Category
Growth Factors & Receptors
Immunohistochemistry Analysis: A previous lot was used by an independent laboratory in IH(P) (Venkateswaran, S., et al)
Research Category
Signaling

质量

Evaluated by Western Blotting in NIH/3T3 cell lysate.
Western Blotting Analysis: 0.78 ?g/mL of this antibody detected Fibroblast Growth Factor Receptor 1 in 10 ?g of NIH/3T3 cell lysate.

目标描述

~92 kDa

联系

Replaces: MAB125

外形

Format: Purified
Protein A purified
Purified mouse monoclonal IgM in 0.015 M potassium phosphate buffer containing 0.15 M NaCl, 0.1% sodium azide, pH 7.20.

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
NIH/3T3 cell lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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