17:0(2S-OH) Ceramide

半岛bd体育手机客户端 说明

一般描述

Ceramides with 2-hydroxy fatty acids (hFA) group are mainly found in the epidermis. 17:0(2S-OH) Ceramide is a unique ceramide containing 17C long chain base fatty acid (heptadecanoic acid)-with 2′-hydroxyl group inSconfiguration.

生化/生理作用

Hydroxy fatty acids (hFA)-sphingolipids helps in cell signaling. They also facilitate cell differentiation and apoptosis. hFA-ceramides in epidermis helps in permeability barrier function. hFA-ceramides are synthesized by fatty acid 2-hydroxylase (FA2H). Mutations of FA2H leads to the development of neurological disorders such as leukodystrophy and spastic paraparesis in humans. hFA-ceramides in the cell membrane are essential for PM02734 drug to exhibit its anti-tumor activity.

包装

5 mL Amber Glass Screw Cap Vial (860818P-5mg)

基本信息

经验(实验)分子式	C35H69NO4
分子量	567.93
NACRES	NA.25

半岛bd体育手机客户端 性质

形式	powder
包装	pkg of 1 × 5 mg (860818P-5mg)
manufacturer/tradename	Avanti Polar Lipids 860818P
运输	dry ice
储存温度	?20℃
SMILES string	CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC([C@@H](O)CCCCCCCCCCCCCCC)=O)CO

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3