16:0(2S-OH) Ceramide

半岛bd体育手机客户端 说明

一般描述

Ceramides with 2-hydroxy fatty acids (hFA) group are present in the epidermis. 16:0(2S-OH) Ceramide is a unique ceramide containing 16C long chain base fatty acid (palmitic acid)-with 2′-hydroxyl group inSconfiguration.

生化/生理作用

Hydroxy fatty acid (hFA)-sphingolipids are implicated in cell signaling. They also facilitate cell differentiation and apoptosis. hFA-ceramides in epidermis help in permeability barrier function. hFA-ceramides are synthesized by fatty acid 2-hydroxylase (FA2H). Mutations of FA2H leads to the development of neurological disorders including leukodystrophy and spastic paraparesis in humans. hFA-ceramides in the cell membrane are essential for PM02734 drug to exhibit its anti-tumor activity.

包装

5 mL Amber Glass Screw Cap Vial (860816P-5mg)

基本信息

经验(实验)分子式	C34H67NO4
分子量	553.90
NACRES	NA.25

半岛bd体育手机客户端 性质

形式	powder
包装	pkg of 1 × 5 mg (860816P-5mg)
manufacturer/tradename	Avanti Polar Lipids 860816P
运输	dry ice
储存温度	?20℃
SMILES string	CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC([C@@H](O)CCCCCCCCCCCCCC)=O)CO

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3