12:0(2S-OH) Ceramide

半岛bd体育手机客户端 说明

一般描述

Ceramides with 2-hydroxy fatty acids (hFA) group are present in the epidermis. 12:0(2S-OH) Ceramide is a 2Shydroxylated lauric acid-containing ceramide.

生化/生理作用

Hydroxy fatty acid (hFA)-sphingolipids facilitate cell signaling. hFA-ceramides contribute to the permeability barrier function of the epidermis. Synthesis of hFA-ceramides are catalyzed by fatty acid 2-hydroxylase (FA2H). Mutations of FA2H causes nervous system disorders leukodystrophy and spastic paraparesis in humans. An antitumor drug, PM02734 requires hFA-ceramides in the cell membrane to exhibit its activity.

包装

5 mL Amber Glass Screw Cap Vial (860812P-5mg)

基本信息

经验(实验)分子式	C30H59NO4
分子量	497.79
NACRES	NA.25

半岛bd体育手机客户端 性质

形式	powder
包装	pkg of 1 × 5 mg (860812P-5mg)
manufacturer/tradename	Avanti Polar Lipids 860812P
运输	dry ice
储存温度	?20℃
SMILES string	CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC([C@@H](O)CCCCCCCCCC)=O)CO

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3