1-O-Acyl-Ceramide

半岛bd体育手机客户端 说明

一般描述

1-O-Acyl-Ceramide is an epidermal ceramide present in mouse and human epidermis. It comprises long chain fatty acids in 1-O-position and is synthesized in the endoplasmic reticulum-related sites.

应用

1-O-Acyl-Ceramide is suitable for use as a lipid standard in

• high performance thin layer chromatography (HPTLC)
• in mass and nuclear magnetic resonance spectroscopy for the quantification of lipids isolated from vernix caseosa skin cream
• in liquid chromatography-tandem mass spectrometry for the quantification of 1-O-Acyl ceramides from liver samples

生化/生理作用

1-O-Acyl-Ceramide functions in maintaining water barrier homeostasis. Deficiency of the glucosylceramide synthase enzyme leads to the accumulation ofO-acylceramides. Treatment of human monoclonal antibody, REMD 2.59 leads to the accumulation of 1-O-acyl-ceramides in soleus muscle and depletion in liver.

包装

5 mL Amber Glass Screw Cap Vial (860526P-5mg)

基本信息

经验(实验)分子式	C53H101NO4
分子量	816.37
NACRES	NA.25

半岛bd体育手机客户端 性质

形式	powder
包装	pkg of 1 × 5 mg (860526P-5mg)
manufacturer/tradename	Avanti Polar Lipids 860526P
运输	dry ice
储存温度	?20℃
SMILES string	[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3