半岛bd体育手机客户端 说明
生化/生理作用
PTEN, a tumor suppressor, has been implicated in a large number of human tumors and is conserved from humans to worms. Characterization of PTEN protein showed that it is a phosphatase that acts on proteins and on 3-phosphorylated phosphoinositides, and can therefore modulate signal-transduction pathways that involve lipid second messengers. Recent results indicate that at least part of its role is to regulate the activity of the serine/threonine kinase AKT/PKB, and thus influence cell survival signaling. Recombinant PTEN is purified by proprietary chromatographic techniques.
外形
Sterile filtered liquid at 100 μg/ml.
重悬
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
基本信息
| MDL编号 | MFCD03458266 |
| NACRES | NA.32 |
半岛bd体育手机客户端 性质
| 生物来源 | human |
| 重组 | expressed inE. coli |
| 测定 | ≥90% |
| 形式 | liquid |
| 分子量 | ~86.0 kDa |
| 包装 | pkg of 5 μg |
| 储存条件 | avoid repeated freeze/thaw cycles |
| 杂质 | <0.1 EU/μg |
| NCBI登记号 | P60484 |
| 运输 | dry ice |
| 储存温度 | ?70℃ |
| Gene Information | human ... PTEN(5728) |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
