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Ferutinin

品牌
Sigma-Aldrich
CAS
41743-44-6
货号
SML1609
包装型号
规格纯度
≥98% (HPLC)
价格
1746.67 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
41743-44-6
Ferutinin
Ferutinine
4-Hydroxy-benzoic acid (3R,3aS,4S,8aR)-1,2,3,3a,4,5,8,8a-octahydro-3-hydroxy-6,8a-dimethyl-3-(1-methylethyl)-4-azulenyl ester
Tefestrol
4-Oxy-6-(4-oxybenzoyloxy)dauc-8,9-en
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Ferutinin, a daucane phytoestrogen, is found in theFerulagenus. It is a natural terpenoid and a calcium ionophore.

包装

5 mg in glass bottle

生化/生理作用

Ferutinin can suppress tumor development without causing systemic toxicity in various tumor cells and animal cancer models. It possesses estrogenic properties and a protective role against uterine carcinoma. Ferutinin exhibits anti-cancer action in estrogen-dependent breast cancer cells.
Ferutinin is a strong agonist for estrogen receptor (ER)α and agonist/antagonist for Erβ with IC50 values of 33.1 nM for ERα and 180.5 nM for Erβ. It has been shown to have both ionophoretic and apoptotic properties. It increases calcium permeability in the lipid bilayer and has been shown to improve bone regeneration in a rat study. It caused significant regression in tumor size in a mouse colon cancer model.

基本信息

经验(实验)分子式 C22H30O4
分子量 358.47
PubChem化学物质编号 329825495
NACRES NA.77

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥98% (HPLC)
形式 powder
储存条件 protect from light
颜色 white to beige
储存温度 2-8℃
SMILES string CC1=CC[C@](CC[C@@]2(O)C(C)C)(C)[C@@]2([H])[C@@H](OC(C3=CC=C(O)C=C3)=O)C1
InChI 1S/C22H30O4/c1-14(2)22(25)12-11-21(4)10-9-15(3)13-18(19(21)22)26-20(24)16-5-7-17(23)8-6-16/h5-9,14,18-19,23,25H,10-13H2,1-4H3/t18-,19+,21-,22+/m0/s1
InChI key CYSHNJQMYORNJI-YUVXSKOASA-N

安全信息

危险声明 H413
危险分类 Aquatic Chronic 4
储存分类代码 13 - Non Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

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