Ciglitizone

半岛bd体育手机客户端 说明

应用

Ciglitizone has been used as a proliferator-activated receptor γ (PPARγ) agonist:

• to study its effects on cell proliferation in human melanocytes
• to study its effects on pigmentation and migration of human melanocytes

It also may be used to study its effects on cell cycle and apoptosis in monocytic cells.

包装

5 mg in glass insert

生化/生理作用

Ciglitizone belongs to the class of thiazolidinediones and is a peroxisome proliferator-activated receptor γ (PPARγ) agonist. It exhibits anti-diabetic activity. Ciglitizone has the potential to treat tumor necrosis factor α (TNFα)-related apoptosis-inducing ligand (TRAIL)-refractory high-grade urothelial cancers.

特点和优势

This compound was developed by Takeda. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

基本信息

经验(实验)分子式	C18H23NO3S
分子量	333.45
MDL编号	MFCD00865499
PubChem化学物质编号	24892661
NACRES	NA.77

半岛bd体育手机客户端 性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
创始人	Takeda
SMILES string	CC1(CCCCC1)COc2ccc(CC3SC(=O)NC3=O)cc2
InChI	1S/C18H23NO3S/c1-18(9-3-2-4-10-18)12-22-14-7-5-13(6-8-14)11-15-16(20)19-17(21)23-15/h5-8,15H,2-4,9-12H2,1H3,(H,19,20,21)
InChI key	YZFWTZACSRHJQD-UHFFFAOYSA-N
Gene Information	human ... PPARG(5468) mouse ... Pparg(19016)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)