C8 Ceramide (d18:1/8:0)

半岛bd体育手机客户端 说明

一般描述

C8 Ceramide is a short chain ceramide and is cell permeable.

应用

C8 Ceramide (d18:1/8:0) has been used as an internal ceramide standard in electrospray ionization. It has also been used as a substrate for ceramide kinase activity assay. It is suitable for use as a substrate for galactocerebrosidase.

生化/生理作用

C8 Ceramide has anti-tumor functionality. Synthetic liposomal C8 ceramide inhibits hepatocellular carcinoma (HCC). Addition of exogenous C8 ceramide causes necrosis in hepatocytes by decreasing ATP levels and impairing mitochondrial functionality. C8 ceramide inhibition of serine palmitoyl transferase haltsde novosphingolipid biosynthesis. It also acts as chemotherapeutic agent by increasing the reactive oxygen species in lung cancer cells.

包装

5 mL Amber Glass Screw Cap Vial (860508P-5mg)

基本信息

经验(实验)分子式	C26H51NO3
分子量	425.69
NACRES	NA.25

半岛bd体育手机客户端 性质

形式	powder
包装	pkg of 1 × 5 mg (860508P-5mg)
manufacturer/tradename	Avanti Polar Lipids 860508P
运输	dry ice
储存温度	?20℃
SMILES string	OC[C@]([H])(NC(CCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC

安全信息

储存分类代码

13 - Non Combustible Solids