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位置: 首页> 品牌> Sigma-Aldrich> Anti-TATA-box-binding protein Antibody, clone SL30-3-563

Anti-TATA-box-binding protein Antibody, clone SL30-3-563

品牌
Sigma-Aldrich
货号
05-1531
规格纯度
clone SL30-3-563, from mouse
价格
5520.38 *本价格含增值税费
促销
服务
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  • 增值税票
数量
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半岛bd体育手机客户端 名称:
Anti-TATA-box-binding protein Antibody, clone SL30-3-563
TATA box binding protein, Transcription initiation factor TFIID TBP subunit, TATA-binding factor, TATA sequence-binding protein, TATA-box binding protein N-terminal domain, TATA-box factor
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

The TATA-box-binding protein (TBP) is a critical, eukaryotic transcription factor. TBP a part of the RNA polymerase II eukaryotic transcription complex and is required for the transcriptional initiation of RNA polymerases. TBP is considered to be a limiting factor for certain RNA promoters. Expression is ubiquitous, however the highest expression has been observed in testis and ovary. Mutations in TBP result in spinocerebellar ataxia type 17(SCA17), a cerebellar disorder classified as autosomal dominant cerebellar ataxia and characterized by atrophy to the cerebellar and cerebral regions, extrapyramidal signs, and dementia.

特异性

This antibody recognizes TATA-box-binding protein at the N-terminus.

免疫原

GST-tagged recombinant protein corresponding to human TATA-box-binding protein at the N-terminus.
Epitope: N-terminus

应用

Research Sub Category
Transcription Factors
Chromatin Immunoprecipitation Analysis: A previous lot was used by an independent laboratory in U2OS cells. (Denisso, S., et al. (2007). The EMBO Journal. 26:944–954.)
Research Category
Epigenetics & Nuclear Function
Use Anti-TATA-box-binding protein Antibody, clone SL30-3-563 (mouse monoclonal antibody) validated in WB to detect TATA-box-binding protein also known as TATA box binding protein, Transcription initiation factor TFIID TBP subunit.

质量

Evaluated by Western Blot in HeLa cell lysate.
Western Blot Analysis: 0.5 ?g/mL of this antibody detected TATA-box-binding protein on 10 ?g of HeLa cell lysate.

目标描述

~38 kDa observed.

外形

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified
Protein G

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
HeLa cell lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 mouse
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 SL30-3-563, monoclonal
species reactivity human
species reactivity (predicted by homology) mouse (based on 100% sequence homology), rat (based on 100% sequence homology)
technique(s) ChIP: suitable
western blot: suitable
同位素/亚型 IgG1κ
NCBI登记号 NP_003185
UniProt登记号 P20226
运输 wet ice
Gene Information human ... TBP(6908)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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