Anti-Nucleolin Antibody, clone 3G4B2

半岛bd体育手机客户端 说明

一般描述

Nucleolin, also known as C23, is the major nucleolar protein of exponentially growing eukaryotic cells. It is a ubiquitous conserved multi-domain phosphoprotein found in all vertebrate species. Nucleolin contains a specific bipartite nuclear localization signal sequence and three different structural domains. Nucleolin is a multifunctional protein involved in most steps of ribosome biogenesis. Nucleolin has been implicated in chromatin structure, rDNA transcription, rRNA maturation, ribosome assembly, cytokinesis, nucleogenesis, cell proliferation and growth, and
nucleo-cytoplasmic transport. Nucleolin also exhibits autodegradation, DNA and RNA helicase activities, and DNA-dependent ATPase activity. Nucleolin activities may be regulated by proteolysis, methylation, ADPribosylation, and phosphorylation by several kinases, including casein kinase II (CK2), p34cdc2, and protein kinase C-ζ.

特异性

nucleolin

免疫原

Nuclear matrix extract from MDCK cells

应用

Anti-Nucleolin Antibody, clone 3G4B2 is a high quality Mouse Monoclonal Antibody for the detection of Nucleolin & has been validated in IP, WB, ICC.

质量

routinely evaluated by immunoblot on HeLa nuclear extract

目标描述

100kDa

联系

Replaces: MABE466

外形

mouse culture supernatant containing 0.05% sodium azide prior to the addition of glycerol to 30%
Unpurified

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160702
NACRES	NA.41

半岛bd体育手机客户端 性质

质量水平	100
生物来源	mouse
抗体形式	culture supernatant
antibody product type	primary antibodies
克隆	3G4B2, monoclonal
species reactivity	canine, human, monkey
manufacturer/tradename	Upstate?
technique(s)	immunocytochemistry: suitable immunoprecipitation (IP): suitable western blot: suitable
同位素/亚型	IgG
NCBI登记号	NM_005381
UniProt登记号	P19338
运输	dry ice
Gene Information	human ... NCL(4691)

安全信息

储存分类代码	10 - Combustible liquids
WGK	WGK 1