20:0(2R-OH) Ceramide

半岛bd体育手机客户端 说明

一般描述

Ceramides containing 2-hydroxy fatty acids (hFA) group are mainly found in the epidermis. 20:0(2R-OH) Ceramide is a 2Rhydroxylated arachidic acid-containing ceramide.

生化/生理作用

Hydroxy fatty acid (hFA)-sphingolipids play a vital role in cell signaling. hFA-ceramides contribute to the permeability barrier function of the surface epithelium of the skin. Fatty acid 2-hydroxylase (FA2H) catalyzes the synthesis of hFA-ceramides. Impaired function of FA2H causes nervous system disorders leukodystrophy and spastic paraparesis in humans. hFA-ceramides are essential for PM02734, an antitumor drug to exhibit its activity.

包装

5 mL Amber Glass Screw Cap Vial (860819P-5mg)

基本信息

经验(实验)分子式	C38H75NO4
分子量	610.01
NACRES	NA.25

半岛bd体育手机客户端 性质

形式	powder
包装	pkg of 1 × 5 mg (860819P-5mg)
manufacturer/tradename	Avanti Polar Lipids 860819P
运输	dry ice
储存温度	?20℃
SMILES string	CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC([C@H](O)CCCCCCCCCCCCCCCCCC)=O)CO

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3