半岛bd体育手机客户端 说明

一般描述

Protein kinase, cGMP-dependent, type II (PRKG2), also known as type II cGMP-dependent protein kinase (cGK), is encoded by the gene mapped to human chromosome 4q13.1–q21.1.

生化/生理作用

Protein kinase, cGMP-dependent, type II (PRKG2) is implicated in the regulation of intestinal fluid balance in man. The encoded protein plays an essential role in proliferative to hypertrophic transition of growth plate chondrocytes during endochondral ossification. Loss of PRKG2 function is associated with the development of renal cysts, intellectual disability and speech defect. In rodent and bovine models, deletion of the gene leads to dwarfism.

单位定义

One unit will phosphorylate one μmole of VASPtide (RRKVSKQE) per minute at pH 7.4

基本信息

MDL编号	MFCD03444648
NACRES	NA.32

半岛bd体育手机客户端 性质

质量水平	200
重组	expressed in baculovirus infectedSf9 cells
测定	>90% (SDS-PAGE)
形式	solution
specific activity	~0.7 U/mg
UniProt登记号	Q64595
运输	dry ice
储存温度	?20℃
Gene Information	rat ... Prkg2(25523)

安全信息

储存分类代码	10 - Combustible liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable