半岛bd体育手机客户端 说明
生化/生理作用
Potent and selective reversible cyclooxygenase-2 (COX-2) inhibitor (IC50= 0.1 μM, human recombinant); about 300-fold less potent as an inhibitor of human recombinant COX-1. Not as selective with natural ovine COX (IC50= 75 μM for COX-1 and 50 μM for COX-2).
基本信息
| 经验(实验)分子式 | C24H20N3O3Cl |
| 分子量 | 433.89 |
| MDL编号 | MFCD02683393 |
| PubChem化学物质编号 | 329820062 |
| NACRES | NA.77 |
半岛bd体育手机客户端 性质
| 质量水平 | 200 |
| 测定 | ≥98% |
| 形式 | powder |
| 溶解性 | chloroform: 10 mg/mL to clear, colorless to light yellow |
| 运输 | wet ice |
| 储存温度 | ?20℃ |
| SMILES string | COc1ccc2n(c(C)c(CC(=O)Nc3cccnc3)c2c1)C(=O)c4ccc(Cl)cc4 |
| InChI | 1S/C24H20ClN3O3/c1-15-20(13-23(29)27-18-4-3-11-26-14-18)21-12-19(31-2)9-10-22(21)28(15)24(30)16-5-7-17(25)8-6-16/h3-12,14H,13H2,1-2H3,(H,27,29) |
| InChI key | DTAPHQYAZUTCIG-UHFFFAOYSA-N |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich
m.cnreagent.com
