半岛bd体育手机客户端 说明
一般描述
Bone morphogenetic proteins (BMPs) are the members of the TGF-β superfamily and are identified as the critical factors for formation of bone and cartilage. Apart from this BMPs have immune regulatory functions. The cellular effects of BMPs are mediated by a heteromeric complex composed of type I and type II receptors. Among the BMPs, BMP-2 has bone and cartilage inducing abilities. The other important functions of BMP-2 are in heart formation. BMP-2 signaling also involves active cross talk with major pathways such as Smad, MAPK, PI3K and NF-κ B.. Monoclonal Anti-BMP-2 recognizes recombinant BMP-2. It also detects BMP-4 (25% cross reactivity).
特异性
The antibody recognizes recombinant human BMP-2. It shows approximately 25% cross-reactivity with recombinant human BMP-4.
免疫原
recombinant human BMP-2.
应用
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)
Monoclonal Anti-BMP-2 antibody may be used in immunoblotting at a working antibody concentration of 1-2 μg/ml.
外形
Lyophilizd from a 0.2 μm filtered solution in PBS, pH 7.4, with 5% trehalose.
制备说明
Purified using protein G.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| MDL编号 | MFCD02095901 |
| NACRES | NA.41 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | 65529.111, monoclonal |
| 形式 | lyophilized powder |
| species reactivity | human |
| technique(s) | western blot: 1-2 μg/mL |
| 同位素/亚型 | IgG2b |
| UniProt登记号 | P12643 |
| 储存温度 | ?20℃ |
| Gene Information | human ... BMP2(650) |
安全信息
| 危险声明 | H412 |
| 预防措施声明 | P273 - P501 |
| 危险分类 | Aquatic Chronic 3 |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
