Fas Ligand, soluble human

半岛bd体育手机客户端 说明

应用

ED₅₀= 1 ng/ml on A20 cells. Does not require any enhancer, as the modified linker sequence already facilitates the formation of active FasL complexes. rhsSuperFasL^?recognizes its receptor Fas (CD95) of the following species: human, rat, mouse.

生化/生理作用

Fas ligand, a protein belonging to the tumor necrosis factor (TNF) family of cytokines, induces apoptosis in cells expressing the cell membrane receptor Fas (CD95/Apo-1).
Fas ligand has also been shown to be involved in the activation of non-apoptotic pathways including proliferation and NF-κ B activation.

法律信息

SuperFas Ligand is a trademark of Alexis Biochemicals Corp.

基本信息

MDL编号	MFCD01092558
NACRES	NA.56

半岛bd体育手机客户端 性质

质量水平	200
生物来源	human
重组	expressed in HEK 293 cells
测定	≥95% (SDS-GE)
形式	lyophilized powder
分子量	32 kDa by SDS-PAGE (nonglycosylated form, under reducing conditions) 35 kDa by SDS-PAGE (glycosylated form, under reducing conditions)
technique(s)	ligand binding assay: suitable
UniProt登记号	P48023
储存温度	?20℃
Gene Information	human ... FASLG(356)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable