半岛bd体育手机客户端 说明
生化/生理作用
Bavachin is a flavonoid isolated from seeds ofPsoralea corylifolia. It is a phytoestrogen that activates ERα and ERβ (EC50s = 320 and 680 nM, respectively), stimulates osteoblast proliferation and differentiation, and prevents bone loss following ovariectomy in rats.
Bavachin is an inhibitor of acyl coenzyme A: cholesterol acyltransferase (ACAT). The IC50 value of bavachin was reported to be 86.0 μM in ACAT assay system using rat liver microsome.
Bavachin is also reported to increase insulin-induced glucose uptake by differentiated adipocytes and myoblasts.
物理属性
Bavachin is soluble in DMSO at 30 mg/mL. Bavachin is not water soluble.
基本信息
经验(实验)分子式 | C20H20O4 |
分子量 | 324.37 |
MDL编号 | MFCD11617359 |
半岛bd体育手机客户端 性质
测定 | ≥97% (HPLC) |
形式 | powder |
储存温度 | ?20℃ |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H302 + H312 + H332 |
预防措施声明 | P280 - P301 + P312 + P330 - P302 + P352 + P312 - P304 + P340 + P312 |
危险分类 | Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral |
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich