Biotin-SLF

品牌

Sigma-Aldrich

CAS

2230857-85-7

货号

914223

包装型号

5 MG

规格纯度

价格

7526.66 元 *本价格含增值税费

促销

数量

- +

半岛bd体育手机客户端名称：

2230857-85-7
Biotin-SLF
( R)-3-(3,4-Dimethoxyphenyl)-1-(3-(4,18-dioxo-22-((3a S,4 S,6a R)-2-oxohexahydro-1 H-thieno[3,4- d]imidazol-4-yl)-8,11,14-trioxa-5,17-diazadocosanamido)phenyl)propyl ( S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carboxylate
Biotin-conjugated FKBP12WT-directed ligand
Biotin-conjugated SLF ligand
FKBP12WT affinity probe for PROTAC and targeted protein degradation research
Bio-SLF

半岛bd体育手机客户端介绍：

半岛bd体育手机客户端说明

应用

Biotin-SLF (bio-SLF) is an FKBP12^WTaffinity probe useful in chemical biology or targeted protein degradation where FKBP12 is used as a tool protein and its enrichment is required in discovery experiments or assay validation.

Related tools:
Additional bifunctional tools for FKPB12 variants:

dTAG-13 (SML2601) for FKBP12^F36V; and KB02-SLF (914738), KB03-SLF (914975), and KB04-SLF (913715) for FKBP12WT
Cereblon (CRBN) affinity probe: Biotin-Thalidomide (913979)

其他说明

The dTAG system for immediate and target-specific protein degradation

Technology Spotlight: Building PROTAC^?Degraders for Targeted Protein Degradation

法律信息

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

基本信息

经验(实验)分子式	C₅₂H₇₆N₆O₁₃S
分子量	1025.26

半岛bd体育手机客户端性质

形式	powder
质量水平	100
储存温度	?20℃
SMILES string	O=C(CCC(NCCOCCOCCOCCNC(CCCC[C@@H]1SC[C@@](N2)([H])[C@]1([H])NC2=O)=O)=O)NC3=CC([C@H](OC([C@@H]4CCCCN4C(C(C(C)(C)CC)=O)=O)=O)CCC5=CC=C(OC)C(OC)=C5)=CC=C3 O=C(CCC(NCCOCCOCCOCCNC(CCCC[C@@H]1SC[C@@](N2)([H])[C@]1([H])NC2=O)=O)=O)NC3=CC([C@H](OC([C@@H]4CCCCN4C(C(C(C)(C)CC)=O)=O)=O)CCC5=CC=C(OC)C(OC)=C5)=CC=C3

安全信息

储存分类代码	10 - Combustible liquids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable