半岛bd体育手机客户端 说明

一般描述

Iodination of 1,5,6,7-tetrahydro-4H-indol-4-one using 1-chloromethyl-4-fluoro-1,4-diazoniabicyclo[2.2.2]octane bis(tetrafluoroborate) yields α-iodo derivative as the main product.

应用

• Reactant in synthesis of psammopemmin A as antitumor agent
• Reactant in synthesis of a 1,3,4,5-tetrahydrobenzindole β-ketoesters and tricyclic tetrahydrobenzindoles via C-H insertion reactions
• Reactant in preparation of tricyclic indole and dihydroindole derivatives as inhibitors of guanylate cyclase
• Reactant in preparation of condensed pyrroloindoles via Pd-catalyzed intramolecular C-H bond functionalization of (halobenzyl)pyrroles
• Reactant in enantioselective preparation of arylalkenyl indoles via asymmetric C-H insertion of rhodium carbenoids followed by Cope rearrangement-elimination

1,5,6,7-Tetrahydro-4 H-indol-4-one may be used in the preparation of:

• 4-oxo-4,5,6,7-tetrahydro-1H-indole-2-carbonitrile
• methyl 2-(4-oxo-4,5,6,7-tetrahydro-1H-indol-1-yl)acrylate
• 3-(4-oxo-4,5,6,7-tetrahydro-1H-indol-1-yl)propanenitrile
• potent and orally active 5-HT1A agonists, (R)-(+)- and(S)-(-)-1-formyl-6,7,8,9-tetrahydro-N,N-dipropyl-3H-benz[e]indol-8-amines

包装

5 g in glass bottle

基本信息

经验(实验)分子式	C8H9NO
分子量	135.16
MDL编号	MFCD00075438
PubChem化学物质编号	24861947
NACRES	NA.22

半岛bd体育手机客户端 性质

质量水平	100
测定	98%
mp	188-190 ℃ (lit.)
SMILES string	O=C1CCCc2[nH]ccc12
InChI	1S/C8H9NO/c10-8-3-1-2-7-6(8)4-5-9-7/h4-5,9H,1-3H2
InChI key	KASJZXHXXNEULX-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319 - H335
预防措施声明	P302 + P352 - P305 + P351 + P338
危险分类	Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 3
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves