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MG-115-CAS 133407-86-0-Calbiochem

品牌
Sigma-Aldrich
CAS
133407-86-0
货号
474780
规格纯度
Potent reversible proteasome inhibitor (Ki= 21 nM and 35 nM for 20S and 26S proteasome, respectively).
价格
3352.28 *本价格含增值税费
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半岛bd体育手机客户端 名称:
133407-86-0
MG-115-CAS 133407-86-0-Calbiochem
Carbobenzoxy-L-leucyl-L-leucyl-L-norvalinal, Z-LL-Nva-CHO, Proteasome Inhibitor XII
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Potent reversible proteasome inhibitor (Ki= 21 nM and 35 nM for 20S and 26S proteasome, respectively).
Potent reversible proteasome inhibitor (Ki= 21 nM and 35 nM for 20S and 26S proteasome, respectively). Specifically inhibits the chymotrypsin-like activity of the proteasome and induces apoptosis in Rat-1 and PC12 cells.

包装

5 mg in Plastic ampoule

生化/生理作用

Product does not compete with ATP.
Target Ki: 21 nM and 35 nM for 20S and 26S proteasome, respectively
Cell permeable: no
Reversible: yes
Primary Target
20S proteasome

警告

Toxicity: Standard Handling (A)

序列

Z-Leu-Leu-Nva-CHO

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Lopes, U.G., et al. 1997.J. Biol. Chem.272,12893.
Lee, D.H., and Goldberg, A.L. 1996.J. Biol. Chem.271,27280.
Palombella, V.J., et al. 1994.Cell78,773. Rock, K.L., et al. 1994.Cell78,761.
Vinitsky, A., et al. 1992.Biochemistry31,9421.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式 C25H39N3O5
分子量 461.59

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥90% (HPLC)
形式 solid
manufacturer/tradename Calbiochem?
储存条件 OK to freeze
protect from light
颜色 white
溶解性 DMSO: 50 mg/mL
运输 ambient
储存温度 ?20℃

安全信息

储存分类代码 11 - Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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