Luteolin-CAS 491-70-3-Calbiochem

半岛bd体育手机客户端 说明

一般描述

An antioxidant flavonoid and a free radical scavenger. Inhibits rat liver cytosolic glutathione S-transferase activity. Also shows cytotoxic effects on Raji lymphoma cells. Incubation of the non-tumor cell line C3H10T?CL8 with luteolin results in induction of p53 accumulation and apoptosis, with apoptosis occurring at the G₂/M phase of the cell cycle. Also shown to inhibit TPL2 kinase.
An antioxidant flavonoid and a free radical scavenger. Inhibits rat liver cytosolic glutathione S-transferase activity. Also shows cytotoxic effects on Raji lymphoma cells. Incubation of the non-tumor cell line C3H10T1/2CL8 with luteolin results in induction of p53 accumulation and apoptosis, with apoptosis occurring at the G₂/M phase of the cell cycle. Also shown to inhibit TPL2 kinase.

包装

5 mg in Glass bottle
Packaged under inert gas

生化/生理作用

Primary Target
rat liver cytosolic glutathione S-transferase activity
Product does not compete with ATP.
Reversible: no
Cell permeable: no

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 weeks at -20°C.

其他说明

Kim, J.E., et al. 2011.J. Pharmacol. Exp. Ther.in press.
Korkina, L.G., and Afanasev, I.B. 1997.Adv. Pharmacol.38,151.
Plaumann, B., et al. 1996.Oncogene13,1605.
Ramanathan, R., et al. 1994.Free Radic. Biol. Med.16,43.
Shimoi, L., et al. 1994.Carcinogenesis15,2669.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	C15H10O6
分子量	286.24
MDL编号	MFCD00017309

半岛bd体育手机客户端 性质

质量水平	100
测定	≥90% (HPLC)
形式	solid
manufacturer/tradename	Calbiochem?
储存条件	OK to freeze protect from light
颜色	yellow
溶解性	aqueous base: 1.4 mg/mL DMSO: 7 mg/mL ethanol: soluble
运输	ambient
储存温度	2-8℃
InChI	1S/C15H10O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-6,16-19H
InChI key	IQPNAANSBPBGFQ-UHFFFAOYSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable