半岛bd体育手机客户端 说明

一般描述

Recombinant, human interleukin-10 expressed inS. frugiperdainsect cells. Pleiotropic cytokine that can exert either immunosuppressive or immunostimulatory effects on a variety of cell types. Potent modulator of monocyte/macrophage function. Exhibits anti-inflammatory effects by suppressing macrophage proliferation. Human IL-10 has cross-species reactivity and is active in mouse cell lines.
Recombinant, human interleukin-10 expressed inS. frugiperdainsect cells. Pleiotropic cytokine that can exert either immunosuppressive or immunostimulatory effects on a variety of cell types. Potent modulator of monocyte/macrophage function. Exhibits anti-inflammatory effects by suppressing macrophage proliferation. Blocks lipopolysaccharide induction of MMP-2 and MMP-9. Known to reduce neuronal degeneration following CNS injury by blocking glutamate-induced caspase-3 activation. Human IL-10 is also active on murine cell lines.

包装

5 μg in Plastic ampoule

生化/生理作用

ED?? = 0.2-1 ng/ml as measured in a cell proliferation assay using a mouse mast cell line, MC/9.

警告

Toxicity: Standard Handling (A)

外形

Carrier-free.

重悬

Reconstitute in sterile water or buffer to a final concentration of 0.1-1 mg/ml as stock solution. Further dilute in buffer such as PBS, 1% BSA.
Following reconstitution, aliquot and freeze -70°C. Stock solutions are stable for up to 3 months at -70°C. Avoid freeze/thaw cycles of solutions.

其他说明

Bachis, A., et al. 2001.J. Neurosci.21,3104.
Fortunato, S.J., et al. 2001.Obstet. Gynecol.98,284.
Fleming, S.D., et al. 1996.J. Immunol.156,1143.
Wang, C.Q., et al. 1996.J. Cell Physiol.166,305.
Niro, H., et al. 1994.Int. Immunol.6,661.
Moore, K., et al. 1993.Annu. Rev. Immunol.11,165.
Vieira, P., et al. 1991.Proc. Natl. Acad. Sci. USA88,1172.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

半岛bd体育手机客户端 性质

测定	≥95% (SDS-PAGE)
质量水平	100
形式	lyophilized
manufacturer/tradename	Calbiochem?
储存条件	OK to freeze
杂质	<100 pg/μg Endotoxin (pg/μg IL-10)
运输	ambient
储存温度	?70℃

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable