半岛bd体育手机客户端 说明
一般描述
A cyanopyrrolidine compound that acts as a potent DPP IV inhibitor (IC50= 3, 5, 8, and 8 nM in inhibiting rat, human, monkey, and canine DDP IV, respectively). Oral administration of K579 in ratsin vivohas been shown to reduce blood DPP IV activity and augment GLP-1 and insulin response after glucose intake and significantly reduce plasma glucose concentration.
Please note: 328.4 is the anhydrous molecular weight; please refer to the vial label for the lot-specific hydration and molecular weight.
包装
5 mg in Glass bottle
Packaged under inert gas
警告
Toxicity: Standard Handling (A)
其他说明
Takasaki, K., et al. 2004.Eur. J. Pharmacol.505,237.
Takasaki, K., et al. 2004.Eur. J. Pharmacol.486,335.
Takasaki, K., et al. 2004.J. Pharmacol. Sci.95,291.
Please note: 328.4 is the anhydrous molecular weight; please refer to the vial label for the lot-specific hydration and molecular weight.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
经验(实验)分子式 | C17H24N6O |
分子量 | 328.41 |
半岛bd体育手机客户端 性质
质量水平 | 100 |
测定 | ≥97% (HPLC) |
形式 | solid |
manufacturer/tradename | Calbiochem? |
储存条件 | OK to freeze protect from light |
颜色 | light brown |
溶解性 | 1 M HCl: 16 mg/mL DMSO: 32 mg/mL ethanol: 6.5 mg/mL |
运输 | ambient |
储存温度 | 2-8℃ |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich