半岛bd体育手机客户端 说明

一般描述

A broad spectrum potent inhibitor of protein tyrosine phosphatases. Also known to inhibit Na⁺/K⁺ATPase, acid and alkaline phosphatases, phosphofructokinase, and adenylate kinase. Most recently shown to inhibit ATPase activity of the reconstituted binding protein-dependent ATP-Binding Cassette (ABC) transporter for maltose (MalFGK₂) ofSalmonella typhimuriumin the micromolar range. Can be converted to pervanadate by hydrogen peroxide.
A broad spectrum potent inhibitor of protein tyrosine phosphatases. Also known to inhibit Na⁺,K⁺-ATPase, acid and alkaline phosphatases, phosphofructokinase, and adenylate kinase. Also inhibits the ATPase activity of the reconstituted binding protein-dependent ATP-Binding Cassette (ABC) transporter for maltose (MalFGK₂) ofSalmonella typhimuriumin the micromolar range. Can be converted to pervanadate by hydrogen peroxide.

包装

5 g in Plastic ampoule

生化/生理作用

Primary Target
Na⁺,K⁺-ATPase, acid , alkaline phosphatases, phosphofructokinase, and adenylate kinase
Product does not compete with ATP.
Reversible: no
Cell permeable: no

警告

Toxicity: Harmful (C)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Huyer, G., et al. 1997.J. Biol. Chem.272,843.
Hunke, S., et al. 1995.Biochem. Biophys. Res. Commun.216,589.
Levchuck, S.G., et al. 1994.Pediatric Res.37,382A.
Fohr, K.J., et al. 1989.Biochem. J.262,83.
Swarup, G., et al. 1982.Biochem. Biophys. Res. Commun.107,1104.
Seargeant, L.E. and Stinson, R.A. 1979.Biochem. J.181,247.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	Na3O4V
分子量	183.91
MDL编号	MFCD00003511

半岛bd体育手机客户端 性质

质量水平	100
形式	solid
manufacturer/tradename	Calbiochem?
储存条件	OK to freeze
颜色	white to off-white
溶解性	water: 10 mg/mL
运输	ambient
储存温度	10-30℃
InChI	1S/3Na.4O.V/q3*+1;;3*-1;
InChI key	IHIXIJGXTJIKRB-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302
预防措施声明	P264 - P270 - P301 + P312 - P501
危险分类	Acute Tox. 4 Oral
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable