PTP1B Inhibitor-CAS 765317-72-4-Calbiochem

品牌

Sigma-Aldrich

CAS

765317-72-4

货号

539741

包装型号

5 MG, PTP1B Inhibitor, CAS 765317-72-4, is a cell-permeable, selective, reversible and non-competitive allosteric inhibitor of PTP1B (IC?? = 4 ?M and 8 ?M for PTP1B403 and PTP1B298, re

规格纯度

PTP1B Inhibitor, CAS 765317-72-4, is a cell-permeable, selective, reversible and non-competitive allosteric inhibitor of PTP1B (IC₅₀= 4 μM and 8 μM for PTP1B403 and PTP1B298, respectively).

价格

3736.22 元 *本价格含增值税费

促销

数量

- +

半岛bd体育手机客户端名称：

765317-72-4
PTP1B Inhibitor-CAS 765317-72-4-Calbiochem
3-(3,5-Dibromo-4-hydroxy-benzoyl)-2-ethyl-benzofuran-6-sulfonicacid-(4-(thiazol-2-ylsulfamyl)-phenyl)-amide, PTP Inhibitor XXII

半岛bd体育手机客户端介绍：

半岛bd体育手机客户端说明

一般描述

A cell-permeable, selective, reversible, and non-competitive allosteric inhibitor of PTP1B (IC₅₀= 4 ?M and 8 ?M for PTP1B₄₀₃and PTP1B₂₉₈, respectively). Binds to a novel site away from the catalytic pocket and inhibits PTP1B activity by preventing closure of the WPD loop. Also available in InSolution format (Cat. No. 539749.

包装

5 mg in Plastic ampoule
Packaged under inert gas

生化/生理作用

Cell permeable: yes
Target IC₅₀: 4 ?M and 8 ?M for PTP1B403 and PTP1B298, respectively
Product does not compete with ATP.
Primary Target
PTP1B403
Reversible: yes

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

其他说明

Wiesmann, C., et al. 2004.Nat. Struct. Mol. Biol.11,730.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	C₂₆H₁₉Br₂N₃O₇S₃
分子量	741.45

半岛bd体育手机客户端性质

质量水平	100
测定	≥95% (HPLC)
形式	solid
manufacturer/tradename	Calbiochem^?
储存条件	OK to freeze protect from light
颜色	white
溶解性	DMSO: 100 mg/mL ethanol: 5 mg/mL
运输	wet ice
储存温度	?20℃

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable