半岛bd体育手机客户端 说明
一般描述
A cell-permeable dipeptide aldehyde that acts as a specific, potent, slow and tight-binding transition state analog inhibitor of prolyl endopeptidase (Ki= 350 pM and 500 pM for mouse brain and human brain prolyl endopeptidase, respectively). Reported to form a hemiacetal with the active-site serine.
A cell-permeable dipeptide aldehyde that acts as a specific, potent, slow, and tight-binding transition state analog inhibitor of prolyl endopeptidase (Ki= 350 pM and 500 pM for mouse brain and human brain, respectively). Reported to form a hemiacetal with the active site serine of the enzyme.
包装
5 mg in Plastic ampoule
Packaged under inert gas
生化/生理作用
Product does not compete with ATP.
Target Ki: 350 pM and 500 pM for mouse brain and human brain prolyl endopeptidase, respectively
Cell permeable: yes
Primary Target
Mouse brain prolylendooeotidase
Reversible: no
警告
Toxicity: Standard Handling (A)
序列
Z-Pro-Pro-CHO
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
其他说明
Fül?p, V., et al. 1998.Cell94,161.
Kahyaoglu, A., et al. 1997.Biochem. J.322,839.
Bakker, A.V., et al. 1990.Biochem. J.271,559.
Wilk, S., and Orlowski, M. 1983.J. Neurochem.41,69.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C18H22N2O4 |
| 分子量 | 330.38 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 测定 | ≥97% (HPLC) |
| 形式 | oil |
| manufacturer/tradename | Calbiochem? |
| 储存条件 | OK to freeze protect from light |
| 颜色 | colorless to off-white |
| 溶解性 | DMSO: 10 mg/mL DMF: soluble ethyl acetate: soluble |
| 运输 | ambient |
| 储存温度 | ?20℃ |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
