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MyoVin-1-Calbiochem

品牌
Sigma-Aldrich
货号
475984
规格纯度
A pyrazolopyrimidine compound that blocks ADP release from the actomyosin complex and acts as a potent, reversible and uncompetitive inhibitor of actin-stimulated ATPase activity of myosin V.
价格
3654.1 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
MyoVin-1-Calbiochem
Myosin V Inhibitor 1
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

A pyrazolopyrimidine compound that blocks ADP release from the actomyosin complex and acts as a potent, reversible and uncompetitive inhibitor of actin-stimulated ATPase activity of myosin V (Ki= 6.3 and 5.5 ?M by single- and double-headed myosin V). Displays excellent selectivity over myosin II and myosin IV (<10% inhibition at 50 ?M) and only minimally inhibits the kinase activity of Cdk1/B, CHK1, Plk1, Abl, ERK2, CKII and Aurora-B (<10% inhibition at 100 ?M).

包装

5 mg in Glass bottle
Packaged under inert gas

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Islam, K., et al. 2010.Angew. Chem. Int. Ed.49,8484.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式 C29H26N6O3S
分子量 538.62
MDL编号 MFCD32009180

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥95% (HPLC)
形式 powder
manufacturer/tradename Calbiochem?
储存条件 OK to freeze
protect from light
颜色 pale yellow
溶解性 DMSO: 50 mg/mL
运输 ambient
储存温度 ?20℃
SMILES string O=C(C1=CC=CC(SCC2=CC=CC(NC3=NC(NN=C4C5=CC=C(N6CCOCC6)C=C5)=C4C=N3)=C2)=C1)O

安全信息

储存分类代码 11 - Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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