MMP-2/MMP-9 Inhibitor I-CAS 193807-58-8-Calbiochem

半岛bd体育手机客户端 说明

一般描述

A potent inhibitor of MMP-2 (gelatinase A; IC₅₀= 310 nM) and MMP-9 (gelatinase B; IC₅₀= 240 nM).
A potent inhibitor of MMP-2 (IC₅₀= 310 nM) and MMP-9 (IC₅₀= 240 nM). Orally active in animal models of tumor growth and metastasis.

包装

5 mg in Plastic ampoule
Packaged under inert gas

生化/生理作用

Primary Target
MMP-2, MMP-9
Product does not compete with ATP.
Reversible: no
Cell permeable: no
Target IC₅₀: 310 nM and 240 nM against MMP-2 and MMP-9

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

其他说明

Tamura, Y., et al. 1998.J. Med. Chem.41,640.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	C21H19NO4S
分子量	381.44

半岛bd体育手机客户端 性质

质量水平	100
测定	≥95% (HPLC)
形式	solid
manufacturer/tradename	Calbiochem?
储存条件	OK to freeze
颜色	white
溶解性	DMSO: 200 mg/mL
运输	ambient
储存温度	?20℃

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable