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Marimastat-CAS 154039-60-8-Calbiochem

品牌
Sigma-Aldrich
CAS
154039-60-8
货号
444289
规格纯度
An orally active peptidyl hydroxamate-based broad-spectrum MMP inhibitor that targets both the substrate binding site and the active-site Zn2+.
价格
3736.22 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
154039-60-8
Marimastat-CAS 154039-60-8-Calbiochem
(2S,3R)-N 4-((1S)-2,2-Dimethyl-1-((methylamino)carbonyl)propyl)-N 1,2-hydroxy-3-(2-methylpropyl)butanediamide, BB-2516
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

An orally active peptidyl hydroxamate-based broad-spectrum MMP inhibitor (IC50in nM = 5, 6, 200, 20, 2, 1.8 and 3.8 for MMP-1, -2, -3, -7, -8, -14 and TACE, respectively) that targets both the substrate binding site and the active-site Zn2+. Marimastate is widely used in studying the involvement of MMPs in various cellular and pathological processes bothin vitroandin vivo.

包装

5 mg in Plastic ampoule
Packaged under inert gas

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

其他说明

Hansen, H.P., et al. 2002.Int. J. Cancer98,210.
Tsuji, F., et al. 2002.Cytokine17,294.
Barlaam, B., et al. 1999.J. Med. Chem.42,4890.
Whittaker, M., et al. 1999.Chem. Rev.99,2735.
Rasmussen, H.S., and McCann, P.P. 1997.Pharmacol. Ther.75,69.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式 C15H29N3O5
分子量 331.41
MDL编号 MFCD00866242

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥98% (NMR)
形式 solid
manufacturer/tradename Calbiochem?
储存条件 OK to freeze
protect from light
颜色 white
溶解性 DMSO: 15 mg/mL
运输 ambient
储存温度 2-8℃
InChI 1S/C15H29N3O5/c1-8(2)7-9(10(19)13(21)18-23)12(20)17-11(14(22)16-6)15(3,4)5/h8-11,19,23H,7H2,1-6H3,(H,16,22)(H,17,20)(H,18,21)/t9-,10+,11-/m1/s1
InChI key OCSMOTCMPXTDND-OUAUKWLOSA-N

安全信息

储存分类代码 11 - Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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