Interleukin-1β, Mouse, Recombinant,E. coli

半岛bd体育手机客户端 说明

一般描述

Recombinant, mouse interleukin-1β expressed inE. coli. Suppresses apoptosis in rat ovarian follicles. Involved in inflammatory and immune responses and promotes wound healing.
Recombinant, mouse interleukin-1β expressed inE. coli. Suppresses apoptosis in rat ovarian follicles. Involved in inflammatory and immune responses and promotes wound healing. Interleukin-1 is a protein produced by stimulated macrophages and many other cell types. The following biological activities are attributed to IL-1: activation of T cells resulting in the production of IL-2 and expression of IL-2 receptors; initiation of Acute Phase Response by induction of hepatic protein synthesis; increased proteolysis of muscle proteins, amino acid mobilization, and caloric and oxygen utilization; induction of bone resorption; stimulation of fibroblast proliferation; induction of slow-wave sleep; fever production; induction of prostaglandin and leukotriene production; stimulation of thymocyte proliferation; induction of B cell proliferation and maturation and increased immunoglobulin synthesis; induction of collagenase and other proteinases in synovial fibroblasts and articular chrondrocytes, suggesting a role in pathological states such as arthritis; activation of neutrophils. 1 ?g is equivalent to 1.1 x 10⁶WHO units.

包装

5 μg in Plastic ampoule

生化/生理作用

ED??= 5-10 pg/ml as measured in a cell proliferation assay

警告

Toxicity: Standard Handling (A)

外形

Lyophilized from sterile-filtered PBS, 50 ?g BSA/?g IL-1β.

重悬

Reconstitute to a concentration of ≥10 ?g/ml with sterile PBS containing ≥0.1% HSA or BSA.
Following reconstitution, aliquot and freeze (-70°C) for long term storage or refrigerate (4°C) for short-term storage. Avoid freeze/thaw cycles of solutions. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -70°C.

其他说明

Chun, S.Y., et al. 1995.Endocrinology136,3120.
Weidmann, B., et al. 1994.Nature370,434.
Dinarello, C.A., and Wolff, S.M. 1993.N. Engl. J. Med.328,106.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

半岛bd体育手机客户端 性质

质量水平	100
测定	≥97% (SDS-PAGE)
形式	lyophilized
manufacturer/tradename	Calbiochem?
储存条件	OK to freeze
杂质	≤1.0 EU/μg Endotoxin (EU/μg IL-1β)
运输	ambient
储存温度	?70℃

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable