您好,欢迎来到半岛电竞官方网址 ! [ 登录] [ 免费注册]
半岛电竞官方网址
位置: 首页> 品牌> Sigma-Aldrich> HNMPA-(AM)3-CAS 120944-03-8-Calbiochem

HNMPA-(AM)3-CAS 120944-03-8-Calbiochem

品牌
Sigma-Aldrich
CAS
120944-03-8
货号
397100
规格纯度
A cell-permeable analog of HNMPA that yields the parent compound upon cleavage by cytosolic esterases.
价格
2741.8 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
120944-03-8
HNMPA-(AM) 3-CAS 120944-03-8-Calbiochem
Hydroxy-2-naphthalenylmethylphosphonic Acid Trisacetoxymethyl Ester, Pro-drug II
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

A cell-permeable analog of HNMPA that yields the parent compound upon cleavage by cytosolic esterases. Inhibits insulin receptor tyrosine kinase (IC50= 100 ?M) and insulin-stimulated glucose oxidation in isolated rat adipocytes (IC50= 10 ?M). Also reported to inhibit tyrosine autophosphorylation of the human insulin receptor (IC50= 200 ?M).
A cell-permeable analog of HNMPA. Inhibits insulin receptor tyrosine kinase (IC50= 100 mM) and insulin-stimulated glucose oxidation in isolated rat adipocytes (IC50= 10 ?M). Also reported to inhibit tyrosine autophosphorylation of the human insulin receptor (IC50= 200 ?M). It has no effect on PKA (at concentrations up to 1 mM) or PKC (at concentrations up to 420 ?M).

包装

5 mg in Plastic ampoule

生化/生理作用

Cell permeable: yes
Target IC50: 100 ?M and 10 ?M against insulin receptor tyrosine kinase and insulin-stimulated glucose oxidation in isolated rat adipocytes, respectively
Primary Target
tyrosine kinase
Product does not compete with ATP.
Reversible: no

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Baltensperger, K., et al. 1992.Proc. Natl. Acad. Sci. USA89,7885.
Saperstein, R., et al. 1989.Biochemistry28,5694.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式 C20H23O10P
分子量 454.36

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥98% (TLC)
形式 oil
manufacturer/tradename Calbiochem?
储存条件 OK to freeze
颜色 colorless
溶解性 DMSO: 20 mg/mL
ethanol: 20 mg/mL
运输 ambient
储存温度 ?20℃

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

推荐半岛bd体育手机客户端
Baidu
map