eIF-2α Inhibitor II, Sal003-CAS 301359-91-1-Calbiochem

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一般描述

A cell-permeable Salubrinal (Cat. No. 324895) analog that is reported to be more potent and soluble than Salubrinal. In addition to being a useful tool in studying elF2α-mediated cellular processes in culturesin vitro, enhanced elF2α phosphorylation by Sal003 treatment in the brain (40 pmol per animal) is shown to impair long-term memory in micein vivo.
A cell-permeable Salubrinal (Cat. No. 324895) analog that is reported to be more potent and soluble than Salubrinal. In addition to being a useful tool in studying elF2α-mediated cellular processes in culturesin vitro, enhanced elF2α phosphorylation by Sal003 treatment in the brain (40 pmol per animal) is shown to impair long-term memory in micein vivo.

包装

5 mg in Plastic ampoule
Packaged under inert gas

警告

Toxicity: Regulatory Review (Z)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Raven, J.F., et al. 2008.J. Biol. Chem.283,3097.
Baltzis, D., et al. 2007.J. Biol. Chem.282,31675.
Kazemi, S., et al. 2007.Mol. Biol. Cell18,3635.
Costa-Mattioli, M., et al. 2007.Cell129,195.
Robert, F., et al. 2006.Mol. Biol. Cell17,4632.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

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