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IgG2a, Kappa from murine myeloma

品牌
Sigma-Aldrich
货号
M7769
规格纯度
clone UPC 10, ascites fluid, lyophilized powder
价格
5129.06 *本价格含增值税费
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半岛bd体育手机客户端 名称:
IgG2a, Kappa from murine myeloma
Mouse IgG2a-κ
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

The UPC-10 tumor line that produces mouse IgG2a, K is a tetramethylpentadecane (pristane) induced plasmacytoma originated and carried intraperitoneally in BALB/c mice. The hapten binding specificity of the UPC-10 line is for β-2-6-linked fructosan. The ascites produced from the UPC-10 tumor line contains IgG2a, K in addition to normal levels of other mouse immunoglobulins and serum proteins. The ascites fluid is clarified by centrifugation and filtration. IgG2a (immunoglobulin G 2a) is one of the subclasses of rat immunoglobulins, which also include IgG1, IgG2b and IgG2c.

特异性

Antigen Specificity: β-2,6-fructosan
Trace amounts of lambda chain may be present.

免疫原

The UPC-10 tumor line that produces mouse IgG2a, K is a tetramethylpentadecane (pristane) induced plasmacytoma originated and carried intraperitoneally in BALB/c mice.

应用

IgG2a, Kappa from murine myeloma has been used in immunofluorescence and immunohistochemistry.

生化/生理作用

The IgG2a (immunoglobulin G 2a) plays a vital role in stimulating autoimmunity in mice. This gene is expressed at high level during virus infection. IgG2a offers host defence through activation of complement system. This antibody has specificity towards Fc receptors expressed on phagocytes and stimulates antibody-dependent cell mediated cytotoxicity. IgG2a also induces macrophage-mediated opsonophagocytosis, which has been observed in response to influenza virus and leads to its clearance from the infected cells.

外形

The product provided is lyophilized from 0.01 M phosphate buffered saline, pH 7.2, with no preservatives added.

制备说明

Storage and Stability:Store the product at 2-8 ℃. After reconstitution, the solution may be stored frozen in working aliquots. Repeated freezing and thawing is not recommended. If slight turbidity occurs upon prolonged storage clarify the solution by centrifugation before use.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号 MFCD00164800
NACRES NA.46

半岛bd体育手机客户端 性质

质量水平 200
生物来源 mouse
偶联物 unconjugated
抗体形式 ascites fluid
克隆 UPC 10, monoclonal
形式 lyophilized powder
储存温度 2-8℃

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable
个人防护装备 Eyeshields, Gloves, type N95 (US)

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