MMP-2 Inhibitor III-CAS 704888-90-4-Calbiochem

品牌

Sigma-Aldrich

CAS

704888-90-4

货号

444288

包装型号

5 MG, The MMP-2 Inhibitor III, also referenced under CAS 704888-90-4, controls the biological activity of MMP-2. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

规格纯度

The MMP-2 Inhibitor III, also referenced under CAS 704888-90-4, controls the biological activity of MMP-2. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

价格

4224.61 元 *本价格含增值税费

促销

数量

- +

半岛bd体育手机客户端名称：

704888-90-4
MMP-2 Inhibitor III-CAS 704888-90-4-Calbiochem
(2-((Isopropoxy)-(1,1'-biphenyl-4-ylsulfonyl)-amino))-N-hydroxyacetamide

半岛bd体育手机客户端介绍：

半岛bd体育手机客户端说明

一般描述

A cell-permeable biphenylsulfonamido-hydroxamate compound that acts a potent and Zn²⁺-binding site-targeting inhibitor of MMP-2 (IC₅₀= 12 nM). It exhibits good selectivity over MMP-9 and MMP-3 (IC₅₀= 0.2 and 4.5 ?M, respectively) and shows practically no effect towards MMP-1 and MMP-7 (IC₅₀>50 ?M). Shown to effectively suppress the invasiveness of HT1080 sarcoma cells grown on matrigel.

包装

5 mg in Plastic ampoule
Packaged under inert gas

生化/生理作用

Cell permeable: yes
Primary Target
MMP-2
Product does not compete with ATP.
Reversible: no
Target IC₅₀: 12 nM against MMP-2

警告

Toxicity: Irritant (B)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

其他说明

Tuccinardi, T., et al. 2006.Bioorg. Med. Chem.14,4260.
Rossello, A., et al. 2004.Bioorg. Med. Chem.12,2441.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	C₁₇H₂₀N₂O₅S
分子量	364.42

半岛bd体育手机客户端性质

质量水平	100
测定	≥95% (HPLC)
形式	solid
manufacturer/tradename	Calbiochem^?
储存条件	OK to freeze protect from light
颜色	white
溶解性	methanol: 100 mg/mL DMSO: 200 mg/mL
运输	ambient
储存温度	2-8℃

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable