半岛bd体育手机客户端 说明
一般描述
A dual reuptake inhibitor of serotonin-norepinephrine with strong preference to serotonin (Ki= 82 and 2480 nM for SERT and NET respectively). Also inhibits reuptake of dopamine. Used in studies of depression, ADHD, and stress-related anxiety.
生化/生理作用
Primary Target
SERT/NET
包装
Packaged under inert gas
警告
Toxicity: Standard Handling (A)
其他说明
Kaur, J., et al. et al. 2010.J. Pharmacy & Bioallied Sci.2,22.
Aboelwafa, A., et al. 2010.AAPS PharmSciTech.11,1026.
Bernardi, S., et al. 2009. J.Thermal Analysis & Calorimetry.97,729.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
经验(实验)分子式 | C17H27NO2· xHCl |
分子量 | 277.40 (free base basis) |
MDL编号 | MFCD03658865 |
半岛bd体育手机客户端 性质
质量水平 | 100 |
测定 | ≥99% (HPLC) |
形式 | solid |
效能 | 82 nM Ki |
manufacturer/tradename | Calbiochem? |
储存条件 | OK to freeze protect from light |
颜色 | white |
溶解性 | water: 100 mM DMSO: 50 mM |
储存温度 | 2-8℃ |
InChI | 1S/C17H27NO2.ClH/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14;/h7-10,16,19H,4-6,11-13H2,1-3H3;1H |
InChI key | QYRYFNHXARDNFZ-UHFFFAOYSA-N |
安全信息
象形图 | |
危险声明 | H411 |
预防措施声明 | P273 - P391 - P501 |
危险分类 | Aquatic Chronic 2 |
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich