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位置: 首页> 品牌> Sigma-Aldrich> Sumanirole Maleate-CAS 179386-44-8-Calbiochem

Sumanirole Maleate-CAS 179386-44-8-Calbiochem

品牌
Sigma-Aldrich
CAS
179386-44-8
货号
5.05896
包装型号
规格纯度
价格
2280.72 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
179386-44-8
Sumanirole Maleate-CAS 179386-44-8-Calbiochem
Dopamine D 2receptor Agonist, Sumanirole, PNU 95666, PNU95666
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

An extremely selective dopamine D2receptor agonist (Ki= 9 nM). Commonly used in Parkinson′s Disease models and to reproduce cocaine′s discriminative stimulus effects. Sumanirole has greater than 200-fold selectivity for the D2receptor subtype versus the other dopamine receptor subtypes in radioligand binding assays. In cell-based assays, sumanirole is a fully efficacious agonist, with EC50values between 17 and 75 nM. In animals, sumanirole elicits many physiological responses attributed to D2-like receptor function.

警告

Toxicity: Standard Handling (A)

其他说明

Achat-Mendes, C. et al., 2010.J. Pharmacol. Exp. Ther.334,556.
McCall, R. B. et al., 2005.J. Pharmacol. Exp. Ther.314,1248.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式 C11H13N3O · xC4H4O4
分子量 203.24 (free base basis)
MDL编号 MFCD09832637

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥98% (HPLC)
形式 solid
效能 9 nM Ki
manufacturer/tradename Calbiochem?
储存条件 OK to freeze
protect from light
颜色 off-white
溶解性 DMSO: 16 mg/mL
储存温度 ?20℃

安全信息

储存分类代码 11 - Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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