Anti-Brachyury Antibody, clone 3E4.2

半岛bd体育手机客户端 说明

一般描述

The Brachyury protein is a T-box transcription factor that is one of the earliest indicators of mesoderm formation during embryonic development. As the brachyury protein family is essential for the formation of the posterior body in all vertebrates, Brachyury has been shown to be expressed during gastrula and neurula stages, as well as in the developing notochord. Consequently, when mutations occur within the brachyury gene, severe vertebral malformations have been found to occur, as a direct result. In addition, current findings also indicate that the dysregulation of brachyury may also be linked to the formation of chordomas, which are malignant tumors that develop along the spine.

特异性

Reactivity with other species has not been tested.
This monoclonal antibody recognizes the brachyury protein.

免疫原

Synthetic human brachyury peptide, a.a. 224-435.
Epitope: C-terminus

应用

Research Sub Category
Mesenchymal Stem Cells
This Anti-Brachyury Antibody, clone 3E4.2 is validated for use in WB for the detection of Brachyury.
Research Category
Stem Cell Research

质量

Routinely evaluated by Western blot on NT2 cell lysates.
Western Blotting:
Recommended working dilutions are 1:1000.

目标描述

47 kDa

外形

Purified mouse monoclonal IgG1κ in buffer containing PBS with 0.05% sodium azide.
Format: Purified
Protein G Purified

储存及稳定性

Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months. Avoid repeat freeze/thaw cycles.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160702
NACRES	NA.41

半岛bd体育手机客户端 性质

质量水平	100
生物来源	mouse
抗体形式	purified immunoglobulin
antibody product type	primary antibodies
克隆	3E4.2, monoclonal
species reactivity	human
manufacturer/tradename	Upstate?
technique(s)	western blot: suitable
input	sample type mesenchymal stem cell(s)
同位素/亚型	IgG1κ
NCBI登记号	NP_003172
UniProt登记号	O15178
运输	wet ice

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable