MultiScreen Permeability Filter Plate, 0.4 μm, non-sterile

半岛bd体育手机客户端 说明

一般描述

Filter Code: PCF
Increasing drug candidate predictability earlier in the discovery pipeline using non-cell-based assays can improve candidate throughput during the ADME stage. Non-cell-based permeability assays are predictive models for oral absorption of development candidates.
MultiScreen Permeability, MultiScreen-IP, and MultiScreen Acceptor plates support artificial membrane strategies for predicting passive transport.
Membranes have uniform pore structure and density for reliable transport:
- Individual wells minimize candidate cross-talk
- Compatibility with automated liquid handling systems increases throughput
Permeability Assay:
- The MultiScreen Permeability plate has a polycarbonate membrane, which supports a hexane/hexadecane artificial layer for permeability assays.1
PAMPA Assay:
- The MultiScreen-IP plate has a hydrophobic PVDF membrane, which supports a lipid bilayer for PAMPA asays.2,3
MultiScreen Acceptor Plate:
- The MultiScreen Acceptor plate can be used with either plate to capture passively transported compounds. Constructed of 100% PTFE, the plate can improve LC/MS results depending on the charge of the small molecules being evaluated.

应用

Research Category
Assays

Protein

外形

Color Code: 透明

其他说明

Automation Compatible: No

法律信息

MULTISCREEN is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

eCl@ss	32039006
NACRES	NB.22

半岛bd体育手机客户端 性质

物料	flat bottom wells polycarbonate membrane polystyrene
质量水平	400
无菌性	non-sterile
半岛bd体育手机客户端 线	MultiScreen?
特点	lid
manufacturer/tradename	MultiScreen?
technique(s)	DNA purification: suitable activity assay: suitable (with precipitations) ligand binding assay: suitable parallel artificial membrane permeation assay (PAMPA): suitable receptor binding assay: suitable
板尺寸	96 wells
孔最大体积	300 μL
工作体积	125 μL
孔径	0.4 μm pore size
试验参数	sample volume: 100 μL (per well)
application(s)	sample preparation
运输	ambient