半岛bd体育手机客户端 说明

一般描述

DHQ)₂PHAL is a modified cinchona alkaloid.

应用

(DHQ)₂PHAL may be used in the following processes:

• As a catalyst Asymmetric and chemoselectiveN-allylic alkylation of indoles with Morita-Baylis-Hillman carbonates to form pyrrolo[1,2-a]indole and pyrrolo[3,2,1-ij]quinoline derivatives.
• As a ligand for the osmium catalyzed-Sharpless asymmetric dihydroxylation step of (S)-a-benzoyloxy carboxylic acids multistep synthesis.
• As a ligand for the carbamate based asymmetric aminohydroxylation of styrene derivatives to formN-carbamate protectedR-arylglycinols.

Sharpless 不对称双羟基化的配体，用于由 ( E,E)- 或 ( E,Z)-1,3-二烯酸甲酯不对称制备 syn-3,5-羟基羧酸酯。

包装

500 mg in glass bottle

外形

具有三取代 C=C 键的不饱和酯的不对称双羟基化。

法律信息

经 Shasun Chemicals and Drugs Limited 授权销售。

基本信息

经验(实验)分子式	C48H54N6O4
分子量	778.98
Beilstein	5475677
MDL编号	MFCD00191975
PubChem化学物质编号	24864480
NACRES	NA.22

半岛bd体育手机客户端 性质

质量水平	200
测定	≥95%
旋光性	[α]22/D +336°, c = 1.2 in methanol
mp	178 ℃ (dec.) (lit.)
SMILES string	CC[C@@H]1CN2CCC1CC2[C@H](Oc3nnc(O[C@@H](C4CC5CCN4C[C@@H]5CC)c6ccnc7ccc(OC)cc67)c8ccccc38)c9ccnc%10ccc(OC)cc9%10
InChI	1S/C48H54N6O4/c1-5-29-27-53-21-17-31(29)23-43(53)45(35-15-19-49-41-13-11-33(55-3)25-39(35)41)57-47-37-9-7-8-10-38(37)48(52-51-47)58-46(44-24-32-18-22-54(44)28-30(32)6-2)36-16-20-50-42-14-12-34(56-4)26-40(36)42/h7-16,19-20,25-26,29-32,43-46H,5-6,17-18,21-24,27-28H2,1-4H3/t29-,30+,31-,32+,43-,44-,45-,46-/m1/s1
InChI key	YUCBLVFHJWOYDN-PPIALRKJSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H317
预防措施声明	P280 - P302 + P352
危险分类	Skin Sens. 1
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Faceshields, Gloves, type N95 (US)