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Interleukin-12 human

品牌
Sigma-Aldrich
货号
H7666
规格纯度
HumanKine?, recombinant, expressed in HEK 293 cells, suitable for cell culture, endotoxin, tested
价格
6820.68 *本价格含增值税费
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半岛bd体育手机客户端 名称:
Interleukin-12 human
IL-12
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

应用

Interleukin-12 (IL-12) human has been used to study IL-12 mediated enhancement of IL-12Rβ2 (IL-12 receptor) expression.

生化/生理作用

Interleukin-12 (IL-12) was identified as a factor secreted by human Epstein-Barr (EBV)-transformed B cell lines. IL-12, or Natural Killer Cell Stimulatory Factor (NKSF), is a 75 kDa disulfide-linked heterodimer of a 35 kDa subunit and 40 kDa subunit. IL-12 is produced predominantly by monocytes and NK cells and induces T cells and NK cells to produce IFN-γ. Human IL-12 is not active on mouse cells, but murine IL-12 is active on both murine and human lymphocytes. The biological activity of recombinant human IL-12 was measured by its ability to stimulate the proliferation of PHA-activated human T lymphoblasts. IL-12 has anti-angiogenic properties.

外形

lyophilized from a 0.2 μm filtered solution of PBS

分析说明

The specific activity was determined by the dose-dependent release of IFN-γ from the human NK92 cell line in presence of 20 ng/mL rIL-2.

法律信息

HumanKine is a registered trademark of Proteintech Group, Inc.

基本信息

MDL编号 MFCD00212975
NACRES NA.77

半岛bd体育手机客户端 性质

质量水平 200
生物来源 human
重组 expressed in HEK 293 cells
测定 ≥95% (SDS-PAGE)
形式 lyophilized
效能 ≤2 ng/mL EC50
分子量 dimer 57 kDa (glycosylated)
包装 pkg of 10 μg
technique(s) cell culture | mammalian: suitable
杂质 endotoxin, tested
储存温度 ?20℃

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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