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Interleukin-5 human

品牌
Sigma-Aldrich
货号
I5273
规格纯度
recombinant, expressed in baculovirus infectedSf21 cells, ≥97% (SDS-PAGE), lyophilized powder, suitable for cell culture
价格
1525.5 *本价格含增值税费
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半岛bd体育手机客户端 名称:
Interleukin-5 human
IL-5
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

生化/生理作用

IL-5 (interleukin-5) is a maturation and differentiation factor for eosinophils. Thus, it is associated with allergy and related disorders. IL-5 association with its receptor causes activation of MEK/ERK (mitogen activated protein kinase kinase/extracellular-regulated kinase), p38 MAPK (mitogen activated protein kinase) and JAK/STAT (Janus kinase/signal transducer and activator of transcription) pathways.
Interleukin-5 is a product of activated T lymphocytes and exhibits activity on eosinophils, B cells and thymocytes. Synonyms or biological activities attributed to IL-5 include: EDF (eosinophil differentiating factor), BCGF-II (B cell growth factor-II), TRF (T cell replacing factor), IgA-EF (IgA enhancing factor) and EO-CSF (eosinophil colony stimulating factor). Natural IL-5 is a 45-50 kDa dimeric glycoprotein, although glycosylation is not required for activity. Human and mouse IL-5 exhibit homology at the nucleotide and amino acid levels and show species cross-reactivity.

外形

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 0.1 mg bovine serum albumin.

基本信息

MDL编号 MFCD00163946
NACRES NA.32

半岛bd体育手机客户端 性质

质量水平 200
生物来源 human
重组 expressed in baculovirus infectedSf21 cells
测定 ≥97% (SDS-PAGE)
形式 lyophilized powder
效能 0.1-0.5 ng/mL EC50
分子量 32-34 kDa
包装 pkg of 5 μg
浓度 0.5-10 ng/mL
technique(s) cell culture | mammalian: suitable
杂质 endotoxin, tested
UniProt登记号 P05113
储存温度 ?20℃
Gene Information human ... IL5(3567)

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable
个人防护装备 Eyeshields, Gloves, type N95 (US)

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